Human Cripto/TDGF1/ CRGF (His Tag) recombinant protein

Cat.#: 501492

Description:Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.

Protein Name:Teratocarcinoma-derived growth factor 1

Protein Short Names:CR1; CRIPTO; CRGF; CR; TDGF1

Uniprot ID:P13385

Gene Name:TDGF1; CRIPTO

Source/Expression Host:Human Cells

Expression Plasmid/cDNA:A DNA sequence encoding the human TDGF1 (AAH22393.1) (Met 1-Thr 172) with a C-terminal polyhistidine tag was expressed.

Protein Species:Human

Molecular Weight:The secreted recombinant human TDGF1 comprises 153 amino acids with a predicted molecular mass of 17.4 kDa. As a result of glycosylation, the apparent molecular mass of rhTDGF1 is approximately 25-30 kDa in SDS-PAGE under reducing conditions.

Purity:> 95 % as determined by SDS-PAGE

Activity:Measured by its binding ability in a functional ELISA. Immobilized human TDGF1 at 2 μg/ml (100 μl/well) can bind human ALK4 with a linear range of 0.0068-0.16 μg/ml.

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