Anti-14-3-3 Beta/Zeta antibody (151-200 aa) (STJ91368)

GENERAL INFORMATION

Host:Rabbit

Applications:WB/IHC/IF/ELISA

Reactivity:Human/Mouse/Rat

Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC

 APPLICATIONS.

Short Description :Rabbit polyclonal antibody anti-14-3-3 protein zeta/delta and 14-3-3 protein beta/alpha (151-200 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

PRODUCT PROPERTIES

Clonality :Polyclonal

Conjugation:Unconjugated

Isotype:IgG

Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration:1 mg/mL

Dilution Range:WB 1:500-1:2000

ELISA 1:20000

IF 1:50-200

Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

TARGET INFORMATION

Gene Symbol:YWHAZ/YWHAB

Gene ID:7534/7529

Uniprot ID:1433Z_HUMAN/1433B_HUMAN

Immunogen Region:151-200 aa

Specificity:14-3-3 Beta/Zeta Polyclonal Antibody detects endogenous levels of 14-3-3 Beta/Zeta protein.

Immunogen:The antiserum was produced against synthesized peptide derived from the human YWHAZ at the amino acid range 151-200

ADDITIONAL INFO

Function:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Induces ARHGEF7 activity on RAC1 as well as lamellipodia and membrane ruffle formation. In neurons, regulates spine maturation through the modulation of ARHGEF7 activity.

Protein Name

1.14-3-3 Protein Zeta/Delta

2.Protein KinaseC Inhibitor Protein 1

3.Kcip-1

Database Links

Reactome: R-HSA-111447

Reactome: R-HSA-1445148

Reactome: R-HSA-3769402

Reactome: R-HSA-392517

Reactome: R-HSA-430116

Reactome: R-HSA-450604

Reactome: R-HSA-512988

Reactome: R-HSA-5625740

Reactome: R-HSA-5628897

Reactome: R-HSA-75035

Reactome: R-HSA-9013700

Reactome: R-HSA-9604323

Reactome: R-HSA-9614399

Cellular Localisation

1.Cytoplasm

2.Melanosome

3.Located To Stage I To Stage Iv Melanosomes

Alternative Antibody Names

1.Anti-14-3-3 Protein Zeta/Delta antibody

2.Anti-Protein Kinase C Inhibitor Protein 1 antibody

3.Anti-Kcip-1 antibody

4.Anti-YWHAZ antibody

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