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2025.01.31 16:32

[My Biosource공식 대리점]-anti-MHC Class I antibody :: Mouse MHC Class I Monoclonal Antibody,anti-MHC Class I antibody: 항-MHC 클래스 I 항체 Mouse MHC Class I Monoclonal Antibody: 마우스 MHC 클래스 I 단클론 항체(MBS140072)

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anti-MHC Class I antibody : Mouse MHC Class I Monoclonal Antibody
CATALOG # : MBS140072
Product Name:MHC Class I, Monoclonal Antibody 
Full Product Name:Mouse Anti MHC Class I (H-2K)
Product Synonym Names:MHC Class I, H-2K Antibody; MHC Class I, (H-2K) Mouse Antibody
Product Gene Name:anti-MHC Class I antibody​
For Research Use Only. Not for use in diagnostic procedures.
Molecular Weight:26,573 Da
Clonality:Monoclonal
Isotype:IgG2b
Clone Number:NYRmH-2K
Host:Mouse
Specificity:Recognizes most mouse H-2K haplotypes (k,p,q,r,s). Does NOT react with H-2kd.
Purity/Purification:Ion exchange column.
Concentration:1mg/ml in PBS (after reconstitution). (lot specific)
Reconstitution:Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Immunogen:Purified mouse LN cells (C57Bl/6 anti-BALB/c).
Antibody Properties:Cytotoxic and staining antibody. For staining, use 10ml/1,000,000 cells. 
Titer for cytotoxicity should be determined by the investigator.
Preparation and Storage
Lyophilized: store at 4 degree C. After reconstitution, if not intended for use within a month,
aliquot and store at -20 degree C.
Other Notes
Small volumes of anti-MHC Class I antibody vial(s) may occasionally become entrapped 
in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge 
the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products 
may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for anti-MHC Class I antibody

Introduction: MHC Class I is a membrane spanning molecule consisting of 2 proteins. MHC Class I is just about 350 amino acids in length,
 with roughly 75 amino acids at the carboxylic end comprising the transmembrane and cytoplasmic portions. The remaining 270 amino 
acids, are divided into three globular domains labeled Alpha-1, Alpha-2 and Alpha-3 prime, with Alpha-1 being closest to the amino 
terminus and Alpha-3 closest to the membrane. The second portion of the molecule is a small globular protein called Beta-2 
Microglobulin It links primarily with the Alpha-3 prime domain and is essential for MHC stability. The MHC ability to show 
a vast range of antigenic peptides for T cell recognition needs a compromise between broad specificity and high affinity. Both 
MHC class I and MHC class II show an exceptional structure while the peptide main chain is tightly bound and peptide 
side chains show less restrictive interactions. It is primarily the peptide side-chain contacts and conformational variability 
that ensures that the peptide-MHC complex presents an antigenically unique surface to T cell receptors.

Product Categories/Family for anti-MHC Class I antibody,Monoclonal/Polyclonal Antibodies; Monoclonal Antibodies, 
NCBI/Uniprot data below describe general gene information for MHC Class I. It may not necessarily be applicable to this product.
NCBI GI #:82123757
NCBI Accession #:O98279
NCBI Official Full Name:MHC class I
UniProt Protein Name:MHC class I
UniProt Synonym Protein Names:MHC class I
Protein Family:Myosin
UniProt Gene Name:gamr-UA-c24  
UniProt Entry Name:O98279_GADMO
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics,
prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you
 will properly test and use any Products purchased from MyBioSource in accordance with industry standards. 
MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably 
believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource
 will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes
to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days 
of receipt of the product. Please visit our Terms & Conditions page for more information.
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