Heparin Unsaturated Disaccharides

Unsaturated Heparin Disaccharide Standards

For disaccharide analysis of heparin and heparan sulphate.

Suitable for USP Chemical Tests / ⟨207⟩ 1,6-Anhydro Derivative for Enoxaparin Sodium

The unsaturated heparin disaccharides are produced by the action of bacterial heparinase enzymes on porcine Heparin and isolated by high resolution gel filtration and ion exchange chromotography.

Enzyme action result in a C4-C5 double bond in uronic acid (∆UA) that absorbs at 232 nm.

The product range includes N-unsubstituted disaccharides (HD010 – HD013)

Heparin Disaccharide Standard Mix (HD Mix) – please email info@iduron.co.uk for further information

Convenient and ready to use the HD Mix is provided as a predissolved aqueous solution of heparin disaccharides HD001, HD002, HD003, HD004, HD005, HD006, HD007 and HD008.

The Heparin Disaccharide Standard Mix (HD Mix) contains enough solution for 10 x 100µl applications. The profile below shows a typical separation of the disaccharides standards. (The exact salt concentration required to elute each sample will vary with column type and manufacture.)

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