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2025.01.30 17:29

[Focus Biomolecules 공식 대리점] Pyrintegrin | ß1-integrin agonist,파이린테그린 | ß1-인테그린 작용제(10-5468) CAS: 1228445-38-2

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Pyrintegrin | ß1-integrin agonist

CAS: 1228445-38-2
Catalog Number: 10-5468

Pyrintegrin (1228445-38-2) is a β1-integrin agonist that promotes survival of human embryonic stem cells following enzymatic dissociation by enhancing cell-ECM-mediated integrin activity.1 It induces soft tissue formation from transplanted or endogenous cells via stimulation of adipogenesis and may have potential in soft tissue therapeutic reconstruction and augmentation2, It protects podocytes from LPS-induced injury in vivo3. A very useful tool for exploring the involvement of β1-integrin signaling in cellular physiology.4,5

Pyrintegrin (1228445-38-2)은 β1-인테그린(β1-integrin) 작용제로, 세포-세포외기질(ECM) 상호작용을 통한 인테그린 활성 증가를 통해 효소적 해리 후 인간 배아줄기세포의 생존을 촉진합니다.¹

또한 지방 형성을 자극하여 이식된 세포 또는 내인성 세포로부터 연조직 생성을 유도하며, 연조직 치료적 재건 및 증강에 활용될 가능성이 있습니다.²

추가적으로, LPS(지질다당류)로 유도된 신장 발세포(podocyte) 손상을 생체 내에서 보호하는 역할을 합니다.³

β1-인테그린 신호전달이 세포 생리학에 미치는 영향을 연구하는 데 매우 유용한 도구입니다.⁴,⁵


CAS:1228445-38-2
Catalog Number:10-5468
Activity:ß1-integrin agonist
Chemical Names:N-(Cyclopropylmethyl)-4-[[4-(3,4-dihydro-6-hydroxy-1(2H)-quinolinyl)-2-pyrimidinyl]amino]-benzenesulfonamide
Molecular Weight:451.54
Molecular Formula:C23H25N5O3S
Solubility:Soluble in DMSO (45 mg/ml)
Physical Properties:White solid
Purity:>98% HPLC
NMR: (Conforms)
Storage Temperature:-20°C
Stability:Stable for up to 2 years when stored as supplied @ -20°C. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:RT

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