Dehydrozingerone | Glutathione sponge

CAS: 1080-12-2

Catalog Number:10-2526

Dehydrozingerone (1080-12-2) is a structural half analog of curcumin (Cat.# 10-1243) and is isolated from ginger rhizomes. 

Dehydrozingerone displays antioxidant, antibacterial and antifungal properties.1 It has also been shown to possess 

various antitumor effects2,3 and inhibit growth factor/peroxide-stimulated vascular smooth muscle function4.

Activity:Glutathione sponge

Chemical Name:(E)-4-(4-Hydroxy-3-methoxyphenyl)but-3-ene-2-one

Molecular Weight:192.21

Molecular Formula:C11H12O3

Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).

Physical Properties:Pale yellow solid

Purity:98% by TLC

NMR (Conforms)

Storage Temperature:-20°

Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored 

at -20° for up to 1 month.

Shipping Code:RT

Safety Data Sheet:N/A

Product Data Sheet:

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References/Citations:

1) Kubra et al. (2014), Structure-function activity of dehydrozingerone and its derivatives as antioxidant and antimicrobial 

compounds; J. Food Sci. Technol., 51 245

2) Motohashi et al. (1998), Inhibitory effects of dehydrozingerone and related compounds on 12-O-tetradecanoylphorbol-

13-acetate induced Epstein-Barr virus early antigen activation; Cancer Lett., 134 37

3) Yogosawa et al. (2012), Dehydrozingerone, a structural analog of curcumin, induces cell-cycle arrest at the G2/M phase 

and accumulates intracellular ROS in HT-29 human colon cancer cells; J. Nat. Prod., 75 2088

4) Liu et al. (2008), Inhibitory effect of dehydrozingerone on vascular smooth muscle cell function; J. Cardiovasc. Pharmacol., 52 422