Y-shape PEG Acetaldehyde 

SKU: Y-AALD

Categories: Activated PEGs for N-terminal PEGylation, Activated Y-Shape PEGs, PEGs WITH ALDEHYDE

Description

Y-shape PEG Acetaldehyde with superior quality specification of ≥95% Substitution.

Y-shape PEG Acetaldehyde from JenKem Technology is an Y-shaped N-terminal reactive 2arm PEG. JenKem proprietary Y-shape PEGs are more selective than linear PEGs, due to their sterically bulky structure. Y-shaped Acetaldehyde PEGs react with N-terminal amines in the presence of a reducing reagent at pH 5-8.

JenKem Technology offers Y-shape PEG Acetaldehyde with MW 40000, in 1g and 10g packing sizes. Different MW of Y-shape PEG Acetaldehyde products may be available by custom synthesis, please email us at tech@jenkemusa.com for details on custom PEGs. JenKem Technology provides repackaging services for an additional fee, please contact us if you require a different package size than our catalog selection.

Bulk PEGs and GMP grade PEGs are made-to-order. Please contact us for bulk pricing.

References:

1. Lorey, S., et al, Novel Ubiquitin-derived High Affinity Binding Proteins with Tumor Targeting Properties, The Journal of Biological Chemistry, 2014, 289,8493-8507.

2. Farkas, T, et al., Additional Studies in the Separation of PEGylated Proteins by Reversed Phase Chromatography, LC/GC, 2008.

Founded in 2001 by experts in PEG synthesis and PEGylation, JenKem Technology specializes exclusively in the development and manufacturing of high quality polyethylene glycol (PEG) products and derivatives, and related custom synthesis and PEGylation services. JenKem Technology is ISO 9001 and ISO 13485 certified, and adheres to ICH Q7A guidelines for GMP manufacture. The production of JenKem® PEGs is back-integrated to in-house polymerization directly from ethylene oxide, enabling facile traceability for regulated customers. JenKem Technology caters to the PEGylation needs of the pharmaceutical, biotechnology, medical device and diagnostics, and emerging chemical specialty markets, from laboratory scale through large commercial scale.