17-AAG 

Catalog Number:HB3599

Product overview

Name:17-AAG

Alternative names:Tanespimycin

Purity:>98%

Description:Selective Hsp90 inhibitor. Also protects neuroprogenitor cells against apoptosis.

Biological Data

Biological description:Selective Hsp90 inhibitor. Potent, less toxic analog of geldanamycin. Also a telomerase activity inhibitor. Shows antitumor activity and induces apoptosis. Also protects neuroprogenitor cells against apoptosis.

Solubility & Handling

Solubility overview:Soluble in DMSO (100 mM)

Storage instructions:-20°C

Storage of solutions:Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.

Shipping Conditions:Stable for ambient temperature shipping. Follow storage instructions on receipt.

Important:This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Chemical Data

Purity:>98%

Chemical name:17-Demethoxy-17-(2-propenylamino)geldanamycin

Molecular Weight:585.7

Molecular Formula:C31H43N3O8

CAS Number:75747-14-7

PubChem identifier:433449

SMILES:CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)C)OC)OC(=O)N)C)C)O)OC

InChiKey:AYUNIORJHRXIBJ-TXHRRWQRSA-N

MDL number:MFCD04973892

Appearance:Purple