Transfected Stable Cell Lines 

Human BRCA1 Knockout Cell Line

Species:Human

Cat.No:ABC-KH0081C

Quality Control:All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category:Transfected Stable Cell Lines

Size/Quantity:1 vial

Shipping Info:Dry Ice

Growth Conditions:37 °C, 5% CO2

Biosafety Level:1

Storage:Liquid Nitrogen

Product Type:Knockout Stable Cell Line

Host Cell:HEK293; Hep G2 or other Cell Lines

Description

BRCA1 Knockout Cell Line is a genetically engineered model derived from different host cell lines based on customers’ requirement. Among various options, HEK293, a human embryonic kidney cell line, is one of the most commonly selected parental cell line. BRCA1 knockout line is usually generated via CRISPR/Cas9-mediated gene editing. The edited cells are maintained at low passage numbers (<P20). Knockout clone is validated either at gene level or protein level by PCR, Sanger Sequencing or Western Blot. Target The BRCA1 gene encodes a tumor suppressor protein that plays a central role in DNA damage repair, cell cycle checkpoint control, and genome stability. BRCA1 loss is associated with increased risk of breast, ovarian, and other cancers due to impaired homologous recombination repair and genomic instability.

견적 문의: aibiohub@aibiohub.co.kr
 홈페이지: www.aibiohub.co.kr   

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