Adefovir Dipivoxil 

Adefovir is a nucleotide analog reverse transcriptase inhibitor (NtRTI) used primarily in the treatment of chronic hepatitis B virus (HBV) infection. Chemically, it is an acyclic nucleotide analog of adenosine monophosphate (AMP). Adefovir works by inhibiting the reverse transcriptase enzyme of HBV, thereby blocking viral replication and reducing the viral load in infected individuals. It is typically administered orally as a prodrug, adefovir dipivoxil, which is rapidly converted to adefovir in the body. Adefovir has demonstrated efficacy in suppressing HBV replication and improving liver function markers in patients with chronic HBV infection. However, prolonged use may lead to the development of drug-resistant HBV strains, necessitating careful monitoring and combination therapy approaches to minimize resistance emergence.

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CAT. No.:CP-A172000

CAS. No.:142340-99-6

Mol. F.:C20H32N5O8P

Mol. Wt.:501.48

Stock Status:Custom Synthesis

Rel. Cas No:220350-60-7 (HBr salt) ; 220350-52-7 (Sulfate salt) ; 220350-68-5 (HCl salt)

Synonyms:NA

Chemical Name:((((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphoryl)bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate)

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